van Wezel Lab: Control of Growth, Cell Division and of Antibiotic Production in Streptomyces

Focus of my research is to provide novel insight into the complex regulatory pathways that control growth, development and antibiotic production of filamentous actinomycetes, and apply this knowledge for improved commercialization of these important industrial microorganisms. A major driving force behind my research is the strong resonance between fundamental and applied research, which in my view should be mutually supportive and cross-feeding.

The main Research Lines of my group are:

  1. Discovery of novel antimicrobials
  2. Nutrient sensing and global control of antibiotic production
  3. Control of cell division and morphogenesis in streptomycetes
  4. Sugar metabolism and carbon catabolite control